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The National Institute for Health Research Hyperacute Stroke Research Centres and the ENCHANTED trial: the impact of enhanced research infrastructure on trial metrics and patient outcomes.

Health Res Policy Syst · 2019 · PMC6375185 · PMID 30760277

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This also led to broader clinically important benefits in patient outcomes, even after adjustment for differences in minimisation criteria and baseline characteristics, though these did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.