highly significantp ≤ 0.01
Highly significant correlations were observed between AA/DHA (the independent variable) and the radiographic and histological endpoints NAS and US (p ≤ 0.01; Fig. 3A ).
Highly significant correlations were observed between AA/DHA (the independent variable) and the radiographic and histological endpoints NAS and US (p ≤ 0.01; Fig. 3A ).
Conversely, the long-chain metabolite α-13′-OH and its isomer M3 showed a trend toward a decrease after treatment; the opposite was found in the placebo group that showed increased levels of α-13′-COOH at the end of the study (Table 3 ).