A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients.

Clin Epigenetics · 2019 · PMC6381754 · PMID 30786922

Europe PMC DOI

hedged sentences

0.1900

closest p · 3.8× alpha

0.1900

boldest claim

The sentences

a trend towards significancep value = 0.19not close (p > 0.1)

Moreover, differences in TRIP10 methylation showed a trend towards significance between R and NR ( p value = 0.19).

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showed a trendno p-value reported

However, in EVC2 gene ( p value = 0.07), CDKL2 gene ( p value = 0.05), and TLX3 gene ( p value = 0.07), replication was not statistically significant but showed a trend towards a higher level of methylation in NR patients (Fig. 3 a).

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