Whole exome sequencing identifies novel predisposing genes in neural tube defects.

Mol Genet Genomic Med · 2019 · PMC6382446 · PMID 30415495

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closest p

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reached borderline significanceno p-value reported

This enrichment reached borderline significance in a replication cohort supporting the association of this new candidate gene to NTD .

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borderline significantno p-value reported

Using a two‐tailed Poisson test, these data suggest a borderline significant p value of 0.05265 in the replication cohort. 4 DISCUSSION In this study, we conducted WES in five new NTD families affected with both forms of open and closed NTD.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.