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Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice.

Sci Rep · 2019 · PMC6382773 · PMID 30787331

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a strong trendno p-value reported
Imiquimod treatment significantly suppressed IAV-induced peri-bronchiolar inflammation and inflammatory cell infiltration, with a strong trend for reduction in alveolitis.

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