Slowly progressive dementia caused by MAPT R406W mutations: longitudinal report on a new kindred and systematic review.

Alzheimers Res Ther · 2018 · PMC6389050 · PMID 29370822

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CSF examinations Results of CSF examinations were available for three members of the novel Swedish kindred and six reported cases in the literature and showed a trend for increased levels of CSF tau and phosphorylated tau in about half of R406W patients, but normal levels of CSF Aβ 1–42 (Additional file 4 ).

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