Barely Significant
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Gender differences in the prevalence of congenital heart disease in Down's syndrome: a brief meta-analysis.

BMC Med Genet · 2017 · PMC6389118 · PMID 28985718

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a clear trendno p-value reported
Despite such limitations, however, it was possible to show a clear trend of a higher prevalence of CHD (more specifically of AVSD) in the female population with DS.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.