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Epidemiology of carbapenem-resistant Enterobacteriaceae: a 5-year experience at a tertiary care hospital.

Infect Drug Resist · 2019 · PMC6390851 · PMID 30863128

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a significant trendno p-value reported
Overall, our hospital-wide carbapenem consumption also increased, with a significant trend over time and with a significant relationship to the incidence of CRE.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.