Amplification of HetR was higher in patients receiving the lower dose of FLC (800 mg/d) although this difference did not reach statistical significance (5.80 ± 7.78 per day versus 1.76 ± 2.62 per day, P = 0.19) ( Figure 5B ).
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Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis.
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