Mesalamine and azathioprine modulate junctional complexes and restore epithelial barrier function in intestinal inflammation.

Sci Rep · 2019 · PMC6391397 · PMID 30809073

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Compared to untreated cells, 5-ASA and AZTP treatment showed a trend for an increase in the number of senescent cells in HCEC-1CT (Fig. 4B ).Overall, these observations provide insight on physiological effects of 5-ASA and AZTP on colonic epithelium which might affect cellular response under stress (Fig. 4C ).

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