Single-center retrospective study of the effectiveness and toxicity of the oral iron chelating drugs deferiprone and deferasirox.

PLoS One · 2019 · PMC6392256 · PMID 30811439

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.1000

boldest claim

The sentences

highly significantp < 0.0000002actually significant

Lab values of included intervals ), mean baseline HIC and SF were not different (p < 0.7 and p < 0.2 respectively); overall, HIC and SF worsened during deferiprone treatment (p < 0.001 and p < 0.0003, respectively), and improved during deferasirox treatment (p < 0.001 and p < 0.0001, respectively); follow-up HIC values differing between deferiprone and deferasirox monotherapies were highly significant (p < 0.0000002).

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did not reach statistical significancep < 0.1so close (0.05 < p ≤ 0.1)

In six patients a mean increase of approximately 5 msec in T2* did not reach statistical significance (p < 0.1).

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