Differences between groups did not reach statistical significance in the lower estimated glomerular filtration rate strata, as the magnitude of the risk ratio decreased with worsening GFR, from 10.64 (1.40–81.03) to 5.64 (1.97–16.18) to 1.83 (0.69–4.84).
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Reassessing the Safety Profile of Lesinurad in Combination with Xanthine Oxidase Inhibitor Therapy.
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