Prognostic value of ALDH1 and Nestin in advanced cancer: a systematic meta-analysis with trial sequential analysis.

Ther Adv Med Oncol · 2019 · PMC6393950 · PMID 30833990

Europe PMC DOI

hedged sentence

0.0620

closest p · 1.2× alpha

0.0620

boldest claim

The sentences

showed a trendp = 0.062so close (0.05 < p ≤ 0.1)

Data from four studies with 707 cases showed a trend towards poor OS in breast cancer patients (HR = 1.67, 95% CI = 0.97–2.87, p = 0.062), but no association was found for colorectal cancer (two studies with 99 cases: HR = 2.30, 95% CI = 0.79–6.70, p = 0.129).

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