Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice.

Redox Biol · 2019 · PMC6395945 · PMID 30818124

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did not reach statistical significanceno p-value reported

While these changes did not reach statistical significance due to the variations, these data confirmed that the structures of autophagosomes that enveloped with mitochondria (mitophagosomes) could be detected in APAP-treated mouse livers regardless of the presence of PINK1 or Parkin.

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