Prioritizing Parkinson's disease genes using population-scale transcriptomic data.

We found a highly significant replication (mean R 2 for expression = 0.071; p = 1.3 × 10 −36 ; mean R 2 for splicing = 0.047; p = 2.1 × 10 −29 ), with 50.2% genes and splicing having R 2 > 0.01 (Supplementary Figure 9 ).

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Genes or splicing events that are nominally significant at p < 0.01 for SNP heritability ( cis - h g 2 ) are used for training predictive models (Supplementary Figure 3 ).

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