The caspase-1 inhibitor seemed to also inhibit IL-1 β release ( Figure 5(a) ), although it did not reach statistical significance due to variability among eosinophil donors, including eosinophils from 3 subjects who did not (2 subjects) or only slightly (1 subject with <15% inhibition) responded to the caspase-1 inhibitor.
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Matrix Metalloproteinase-9-Dependent Release of IL-1<i>β</i> by Human Eosinophils.
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