Programmed conversion of hypertrophic chondrocytes into osteoblasts and marrow adipocytes within zebrafish bones.

We have now performed additional transplantation experiments and have increased our n from 2 to 8, which reveal a strong trend toward rescue of adipocyte numbers (revised Figure 7G). “We also observed rescue of marrow adipocyte number by wild-type chondrocytes, though this had moderate statistical significance (p = 0.06), potentially owing to low sample size ( n = 8), the mosaic contribution of wild-type cells to the growt

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