Integrative Analysis of Novel Metabolic Subtypes in Pancreatic Cancer Fosters New Prognostic Biomarkers.

Between the Non-Gly and the Gly subtypes, we identified 763 highly significant Differentially Expressed (DE) genes (Adj. p < 1E-05), 296 of which over-expressed in Gly subtype and 466 over-expressed in the Non-Gly tumors ( Figure 2A and Supplementary Table 3 ).

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Considering BCT and ACT proteins levels separately, respectively 73 and 28 proteins showed a significant trend across samples ( Supplementary Table 8D ).

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Of note, TPI1 concentration increases after CT ( Figure 4B ) and, it was one of the most significant protein (BCT p = 0.0136), with a positive trend increasing from good to bad prognosis patients, both BCT and ACT ( Figure 4C ).

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