Isolation of circulating tumor cells and detection of EGFR mutations in patients with non-small-cell lung cancer.

iii) No significant association was observed between a higher CTC number and tumor burden or smoking status; however, a clear trend toward a correlation between an increased CTC detection rate and increased tumor diameter was observed (<3 cm, 48.7% vs. ≥3 cm, 71.1%; P=0.078).

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