Coronary Endothelial Dysfunction Is Associated With Elevated Serum PCSK9 Levels in People With HIV Independent of Low-Density Lipoprotein Cholesterol.

J Am Heart Assoc · 2018 · PMC6404863 · PMID 30371326

Europe PMC DOI

hedged sentences

0.1012

closest p · 2.0× alpha

0.1012

boldest claim

The sentences

did not reach statistical significanceP =0.1012not close (p > 0.1)

Although there was a trend for an inverse correlation of PCSK9 serum levels with systemic endothelial function ( R =−0.31, R 2 =0.09, CSA=−0.01408 ×PCSK9+9.778), this did not reach statistical significance ( P =0.1012; Figure 4 B).

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highly significantno p-value reported

The inverse relationship between PCSK9 and CEF is strong and highly significant.

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a nonsignificant trendno p-value reported

The small sample size in the HIV− group may have limited the power to detect significant differences; however, we did find a nonsignificant trend between serum PCSK9 and MRI measures of systemic endothelial function.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.