Baumgart et al[ 25 ], and Lasa et al[ 26 ], indicated numerical superiority of tacrolimus versus placebo for induction of clinical remission in UC [odds ratio (OR): 2.27; 95%CI: 0.35-14.75; RR: 0.91; 95%CI: 0.82-1.00, respectively], but the results did not reach statistical significance due to the small number of enrolled patients.
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Conventional therapy for moderate to severe inflammatory bowel disease: A systematic literature review.
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