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A Human Skin Model Recapitulates Systemic Sclerosis Dermal Fibrosis and Identifies COL22A1 as a TGFβ Early Response Gene that Mediates Fibroblast to Myofibroblast Transition.

Genes (Basel) · 2019 · PMC6409682 · PMID 30678304

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COL22A1 silencing reduced TGFβ induction of COL1A1 and to a lesser degree that of FN , but the differences did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.