TAK-071, a muscarinic M1 receptor positive allosteric modulator, attenuates scopolamine-induced quantitative electroencephalogram power spectral changes in cynomolgus monkeys.

Although there was no significant effect on delta power band, a decreasing trend was observed when TAK-071 was administered at 1 and 3 mg/kg ( Fig 4C ).

also in 47,180 other papers

Simultaneous administration of xanomeline (1 mg/kg, s.c.) and scopolamine (25 μg/kg, s.c.) showed a trend to suppress the effects of scopolamine on qEEG power spectral changes ( Fig 3A–3C ).

also in 53,322 other papers