Distributions of Extracellular Peptidases Across Prokaryotic Genomes Reflect Phylogeny and Habitat.

Archaea demonstrated a weakly significant relationship at all taxonomic levels examined, whereas relationships within Bacteria were weakly significant only between taxa that share ≥90% 16S rRNA gene sequence identity, beyond which pairs of taxa share little to no functional similarity in the secreted peptidases they encode ( Supplementary Figure S3 ).

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