Barely Significant
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One-year pilot study on the effects of nitisinone on melanin in patients with OCA-1B.

JCI Insight · 2019 · PMC6413781 · PMID 30674731

Europe PMCDOI
1
hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

moderately significantP = 0.08so close (0.05 < p ≤ 0.1)
Longitudinal models fit using skin reflectometry data through the safety visit revealed a significant increase in pigmentation on the inner bicep (mean [95% CI] change from baseline in M index of 1.72 [0.03, 3.41], P = 0.047) and a moderately significant increase in pigmentation on the outer forearm (mean [95% CI] change from baseline in M index of 3.4 [–0.5, 7.2], P = 0.08) at month 12 compared with baseline.

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