While there was a trend of reduced T1D incidence in Tnfrsf9 B10 compared to Tnfrsf9 NOD F1 mice (p = 0.13 by Log-rank test), the difference did not reach statistical significance (Fig. 4 ).
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Combined congenic mapping and nuclease-based gene targeting for studying allele-specific effects of Tnfrsf9 within the Idd9.3 autoimmune diabetes locus.
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