Urinary Calprotectin loses specificity as tumour marker due to sterile leukocyturia associated with bladder cancer.

PLoS One · 2019 · PMC6417709 · PMID 30870488

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did not reach statistical significanceno p-value reported

A multivariate analysis identified leukocyte concentration to be the only significant impact factor for uC concentration (OR 3.2, 95% CI 2.5–3.8, p = 0.001); age (years) (OR 5.0, 95% CI -10.0–20.0, p = 0.48), gender (male/female) (OR 129.1, 95% CI -324.3–582.6, p = 0.57), and grading (low-grade/high-grade) (OR 110.4, 95% CI -298.0–518.8, p = 0.59) did not reach statistical significance ( Fig 2(B) ).

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