APOLLO-1: a randomized placebo and active-controlled phase III study investigating oliceridine (TRV130), a G protein-biased ligand at the µ-opioid receptor, for management of moderate-to-severe acute pain following bunionectomy.

J Pain Res · 2019 · PMC6417853 · PMID 30881102

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did not reach statistical significanceno p-value reported

19 , 23 However, unlike the earlier results, the differences between groups using this new composite outcome did not reach statistical significance in the APOLLO-1 study population.

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