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Improved mass spectrometry-based activity assay reveals oxidative and metabolic stress as sirtuin-1 regulators.

Redox Biol · 2019 · PMC6423473 · PMID 30877853

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showed a trendno p-value reported
The polyphenol S17834 developed by Servier showed a trend of increased endogenous SirT1 activity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.