Treatment With Acetylsalicylic Acid Reverses Endotoxin Tolerance in Humans In Vivo: A Randomized Placebo-Controlled Study.

Crit Care Med · 2019 · PMC6426341 · PMID 30585832

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did not reach statistical significanceno p-value reported

This effect was similar across all groups and during both endotoxin challenges, although it did not reach statistical significance in the ASA prophylaxis group upon the first endotoxin challenge, which might be another reflection of the enhanced proinflammatory profile observed in this group.

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