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Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology.

Elife · 2019 · PMC6426440 · PMID 30893049

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The cell death associated with chronic intermittent OptoGranule assembly progressed more slowly than the cell death caused by chronic persistent OptoGranule assembly, although this difference did not reach statistical significance ( Figure 3—figure supplement 1a ).

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