AIM2 Inflammasome Activation Leads to IL-1α and TGF-β Release From Exacerbated Chronic Obstructive Pulmonary Disease-Derived Peripheral Blood Mononuclear Cells.

Instead, the stimulation of both healthy- and smoker-derived PBMCs did not reach statistical significance after Poly dA:dT addition ( Figure 3B ), further highlighting the relevance of AIM2 in COPD-associated inflammation.

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