Genotoxic Effects of Tributyltin and Triphenyltin Isothiocyanates, Cognate RXR Ligands: Comparison in Human Breast Carcinoma MCF 7 and MDA-MB-231 Cells.

Although differences in 48 h IC50 values in the MDA-MB-231 cell line did not reach statistical significance, in MCF 7 cells the 48 h IC50s differed significantly and almost doubled for TPT-ITC in comparison with TBT-ITC ( Figure 2 ).

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