Barely Significant
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Are 'dual users' who smoke and use e-cigarettes interested in using varenicline to stop smoking altogether, and can they benefit from it? A cohort study of UK vapers.

BMJ Open · 2019 · PMC6429907 · PMID 30872554

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At the end of the varenicline use period at 3 months, the varenicline group was reporting a significantly greater reduction in enjoyment of vaping, while the difference in reduction of enjoyment of smoking did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.