The NRF2 transcriptional target NQO1 has low mRNA levels in TP53-mutated endometrial carcinomas.

PLoS One · 2019 · PMC6433262 · PMID 30908539

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a strong trendno p-value reported

We have observed a strong trend toward more NRF2 highly stained tumors within the TP53/CNH-like group, known to be of poor prognosis [ 2 ], consistent with previous reports describing higher NRF2 expression with advanced stage and high tumor grade in endometrial carcinomas [ 32 ].

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