In fact, the incubation of BFH12 cells with 100 μM RU486 showed a trend indicative of a mild increase in the recruitment of RXRα (approximately 1.5–3-fold) to either the ER6 motif ( Fig 8A and S9 Fig , panel A and B) than the DR5 motif in the distal F3 fragment ( Fig 8B and S9 Fig , panel C and D) in all experiments even though there was a significant variation among individual reactions.
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DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene.
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