Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease.

Commun Biol · 2019 · PMC6437163 · PMID 30937401

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nominally significantno p-value reported

In our latest study, height-increasing alleles at all 606 height-associated variants (Exome Chip data) were enriched for nominally significant protective effect on several cardiometabolic traits: total cholesterol (TC; P binomial = 4.4 × 10 −8 ), triglyceride (TG; P binomial = 8.9 × 10 −7 ) and coronary artery disease (CAD; P binomial = 6.0 × 10 −10 ).

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