Compared to subcutaneous preadipocytes, the omental preadipocytes showed a trend of increased mRNA expression of CCL2 and IL6 in response to IL1β ( Supplementary Figure 1 ).
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Membrane metallo-endopeptidase (Neprilysin) regulates inflammatory response and insulin signaling in white preadipocytes.
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The levels of biotinylated insulin receptor (biotin-IRβ) showed a decreasing trend in the MME knockdown at 30 min and 120 min ( Figure 7 D).