Synbiotic-driven improvement of metabolic disturbances is associated with changes in the gut microbiome in diet-induced obese mice.

In eAT, except for the genes of leptin and LBP, both the pre- and synbiotic treatments significantly decreased the gene expressions of TNF-a ( Figure 2 C), CD11c ( Figure 2 D), and MCP-1 ( Figure 2 E), while the probiotic treatment did not reach statistical significance.

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