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Dual bronchodilation with tiotropium/olodaterol further reduces activity-related breathlessness <i>versus</i> tiotropium alone in COPD.

Eur Respir J · 2019 · PMC6437647 · PMID 30655277

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The TDI data in the present trial are also similar to those previously published, and although the treatment difference did not reach statistical significance, a clinically important mean improvement of >1 unit [ 16 ] from baseline was observed with tiotropium/olodaterol only.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.