Strain-Dependent Differences in Sensitivity to Myopia-Inducing Stimuli in Guinea Pigs and Role of Choroid.

Although none of the changes (i.e., after either 1 or 5 days of optical defocus) proved to be statistically significant for either strain, curiously over the time frame of this study only the EH strain showed an apparent trend of increased axial elongation after 5 days of optical defocus imposed with negative lenses.

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The above difference in choroidal thickness is consistent with data extracted from OCT images ( Table 2 ), although the equivalent differences derived from OCT images did not reach statistical significance.

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