Regulation of UGT2A1 by miR-196a-5p and miR-196b-5p.

J Pharmacol Exp Ther · 2019 · PMC6439457 · PMID 30850392

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near-significantno p-value reported

For both miR-196a-5p and miR-196b-5p, luciferase activity demonstrated significant or near-significant increases in activity for cells transfected with the UGT2A1 3′-UTR seed deletion mutant as compared with cells transfected with the wild-type UGT2A1 3′-UTR sequence ( P = 0.046 and 0.075 for miR-196a-5p and miR-196b-5p, respectively; Fig. 2A ).

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