Optimization of the treatment with beta-lactam antibiotics in critically ill patients-guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique-SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d'Anesthésie et Réanimation-SFAR).

Crit Care · 2019 · PMC6441232 · PMID 30925922

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a strong trendp = 0.06so close (0.05 < p ≤ 0.1)

Although there was no significant difference in terms of ICU mortality rates between the two methods of administration in this subgroup of most severe patients (RR 0.79 [0.53–1.17]), there was a strong trend towards reducing 30-day hospital mortality with continuous administration (RR 0.74 [0.53–1.01], p = 0.06).

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