Five genes were significantly upregulated between severe preterm and controls when analyzing the qPCR expression data: LCN2, MARCO and TNFSF15 ( p value < 0.001) and CASP5 and IL1B ( p value < 0.05); SERPINA1 was also upregulated, although the differences between groups did not reach statistical significance (Additional file 6 ).
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Transcriptomic analysis of fetal membranes reveals pathways involved in preterm birth.
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