Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

Nat Commun · 2019 · PMC6445072 · PMID 30940813

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

nominally significantno p-value reported

FTO SNPs become only nominally significant for both alcohol-related traits: the p value for the lead SNP for AUDIT-C, rs9937709, decreases in significance from 5.53 × 10 −14 to 1.42 × 10 −5 and for the lead SNP for AUD, rs11075992, it decreases in significance from 3.22 × 10 −10 to 3.02 × 10 −5 .

also in 7,732 other papers

highly significantno p-value reported

We validated the phenotype in a sample of 1851 participants from the Veterans Aging Cohort Study 33 , in which we found a highly significant association of AUDIT-C scores with the plasma concentration of phosphatidylethanol, a direct, quantitative biomarker that is correlated with the level of alcohol consumption.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.