As shown in Figure 8 , TAC and MePRD reduced the secretion of IFNγ significantly by 71.1 ± 24.5% and 95.6 ± 5.5%, respectively; whereas MPA and EVE by 42.4 ± 19.8% and 42.9 ± 15.3%, respectively, CsA-induced changes were barely significant (27.3 ± 12.16%) ( Figure 8A , left panel).
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Small-Molecule Immunosuppressive Drugs and Therapeutic Immunoglobulins Differentially Inhibit NK Cell Effector Functions <i>in vitro</i>.
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In contrast, IVIg showed a trend toward increased IFNγ production and secretion.