Effects of azilsartan compared with telmisartan on insulin resistance in patients with essential hypertension and type 2 diabetes mellitus: An open-label, randomized clinical trial.

The mean (95% CI) changes from the baseline values in HOMA-R at the end of the treatment period were 0.22 (−1.09–1.52) in the azilsartan group and −0.23 (−0.72–0.27) in the telmisartan group, thus indicating that azilsartan and telmisartan did not clinically remarkably improve insulin resistance, although telmisartan showed a trend of slightly decreasing insulin sensitivity.

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