Tbet and Foxp3 expression showed a trend towards correlation with OPN expression ( Fig 3D and 3E ).
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Antibody-mediated targeting of cleavage-specific OPN-T cell interactions.
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The sentences
There was a highly significant reduction in T cells in adipose tissue of Spp1 -/- mice which strongly suggests that OPN is implicated in regulating the number of T cells in adipose tissue.