Effect of ranolazine on plasma arginine derivatives and urinary isoprostane 8-iso-PGF_2α in patients with myocardial infarction in the randomized RIMINI-Trial.

Even though there was no significant difference between baseline and values at the end of the study, 8-iso-PGF 2α concentrations showed a trend to lower values in ranolazine-patients (difference −144 pmol/mg creatinine, 95% CI −355 to 66, P = 0.15, Fig. 1E ), whereas such a trend was missing in the control group.

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