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BIS-guided deep anesthesia decreases short-term postoperative cognitive dysfunction and peripheral inflammation in elderly patients undergoing abdominal surgery.

Brain Behav · 2019 · PMC6456817 · PMID 30815998

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showed a trendno p-value reported
However, it should be noted that NE levels showed a trend increase in the Light group, which may suggest heightened stress responses contributing to the higher level of inflammation evident in this group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.